A novel fluorescent marking clip for laparoscopic surgery of colorectal cancer: A case report

doi:10.1016/j.ijscr.2019.10.024

. 2019:64:170-173.

doi: 10.1016/j.ijscr.2019.10.024. Epub 2019 Oct 17.

A novel fluorescent marking clip for laparoscopic surgery of colorectal cancer: A case report

Affiliations

¹ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: nasa1355@yahoo.co.jp.
² Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: masashi@iuhw.ac.jp.
³ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: hohdaira0428@gmail.com.
⁴ Center for Photodynamic Medicine, Kochi University, Kohasu Oko-cho 185-1, Nankoku, Kochi, 783-8505, Japan. Electronic address: tacsato-kochimed@umin.ac.jp.
⁵ Department of internal medicine, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: daisuto@iuhw.ac.jp.
⁶ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: hoshimoto@iuhw.ac.jp.
⁷ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: norinori_sculler@yahoo.co.jp.
⁸ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: rui2612@yahoo.co.jp.
⁹ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: teppei0911show@yahoo.co.jp.
¹⁰ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: m1141106@mn.med.oita-u.ac.jp.
¹¹ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: yutaka@iuhw.ac.jp.

PMID: 31655290
PMCID: PMC6831794
DOI: 10.1016/j.ijscr.2019.10.024

Free PMC article

A novel fluorescent marking clip for laparoscopic surgery of colorectal cancer: A case report

Satoshi Narihiro et al. Int J Surg Case Rep. 2019.

Free PMC article

. 2019:64:170-173.

doi: 10.1016/j.ijscr.2019.10.024. Epub 2019 Oct 17.

Authors

Affiliations

¹ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: nasa1355@yahoo.co.jp.
² Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: masashi@iuhw.ac.jp.
³ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: hohdaira0428@gmail.com.
⁴ Center for Photodynamic Medicine, Kochi University, Kohasu Oko-cho 185-1, Nankoku, Kochi, 783-8505, Japan. Electronic address: tacsato-kochimed@umin.ac.jp.
⁵ Department of internal medicine, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: daisuto@iuhw.ac.jp.
⁶ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: hoshimoto@iuhw.ac.jp.
⁷ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: norinori_sculler@yahoo.co.jp.
⁸ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: rui2612@yahoo.co.jp.
⁹ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: teppei0911show@yahoo.co.jp.
¹⁰ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: m1141106@mn.med.oita-u.ac.jp.
¹¹ Department of Surgery, International University of Health and Welfare Hospital, 537-3, Iguchi, Nasushiobara City, Tochigi, 329-2763, Japan. Electronic address: yutaka@iuhw.ac.jp.

PMID: 31655290
PMCID: PMC6831794
DOI: 10.1016/j.ijscr.2019.10.024

Abstract

Introduction: In laparoscopic surgery, marking of tumor location has been gaining importance. Tattoo marking has been often used but the technique carries the risk of accidental peritoneal scattering or other organ injury. We have been involved in the development of a novel fluorescent clip for marking tumor sites and supposed that its usage would reduce risks related to other marking methods.

Case presentation: A 52-year-old man was diagnosed with sigmoid colon cancer and polyp, and was scheduled for laparoscopic sigmoidectomy. On the day before operation, fluorescent clips (ZEOCLIP FS: Zeon Medical co, Ltd, Tokyo) were endoscopically placed around the tumor and polyp sites, 4 clips for each lesion attached every 90 degrees within the colonic lumen, respectively. During the operation, locations of the fluorescent clips were easily confirmed using a full-color fluorescent laparoscope, VISION SENSE (Medtronic Co., U.S.). Curative operation was performed accordingly with the preoperative pathological and radiological findings. The postoperative course was uneventful.

Discussion: Locations of intraluminally placed fluorescent clips were clearly and easily recognized through the serosal layer of the intestinal wall using a fluorescent laparoscope. Complications related to dye scattering or intestinal wall/other organ perforation were not observed suggesting that future incorporation of this tumor site marking technique into laparoscopic surgery might be beneficial.

Conclusion: The fluorescent marking clips were easily placed and recognized with a fluorescent laparoscope. This method is expected to be safe and risks of accidental puncture related to tattoo marking method can be reduced or almost eliminated.

Keywords: Colorectal cancer; Fluorescent clip; Tattoo marking; VISION SENSE.

Published by Elsevier Ltd.

PubMed Disclaimer

Figures

**Fig. 1**
A schematic drawing of the fluorescent clip (ZEOCLIP FS) loaded into the cartridge. (Courtesy of Zeon Medical Co., Ltd., Tokyo).

**Fig. 2**
Fluorescent clips (ZEOCLIP FS: Zeon Medical Co., Ltd., Tokyo) placed endoscopically in 4 places every 90 degrees within the colonic lumen.

**Fig. 3**
Intraoperative observation using a full-color fluorescent laparoscope VISION SENSE (Medtronic Co., U.S.) of the serosal layer.

**Fig. 4**
Resected specimen with clips marking the tumor and polyp locations.

See this image and copyright information in PMC

Cited by

Efficacy and Safety of Gastrointestinal Tumour Site Marking with da Vinci-Compatible Near-Infrared Fluorescent Clips: A Case Series.
Takahashi J, Yoshida M, Ohdaira H, Nakaseko Y, Nakashima K, Kamada T, Suzuki N, Sato T, Suzuki Y. Takahashi J, et al. World J Surg. 2023 Oct;47(10):2386-2391. doi: 10.1007/s00268-023-07082-6. Epub 2023 Jun 20. World J Surg. 2023. PMID: 37340097 Free PMC article.
Clip or Tattooing: A Comparative Study for Preoperative Colon Cancer Endoscopic Localization.
Zhang S, Wang Q, Feng Y, Zhang G, Chen Y, Zheng W, Wu X, Yang A. Zhang S, et al. Front Oncol. 2022 Feb 25;12:846900. doi: 10.3389/fonc.2022.846900. eCollection 2022. Front Oncol. 2022. PMID: 35280761 Free PMC article.
Near-infrared fluorescent clip guided gastrectomy: Report of 2 cases (Case reports).
Narihiro S, Yoshida M, Ohdaira H, Takeuchi H, Kamada T, Marukuchi R, Suzuki N, Hoshimoto S, Sato T, Suzuki Y. Narihiro S, et al. Ann Med Surg (Lond). 2020 May 11;55:49-52. doi: 10.1016/j.amsu.2020.04.026. eCollection 2020 Jul. Ann Med Surg (Lond). 2020. PMID: 32461802 Free PMC article.

References

1. Ishihara Soichieo, Kawai Kazushige, Hata Keisuke. Colonoscopy for surgical treatment of colorectal cancer. Gastroenterol. Endosc. 2016;28:1992–1998.
1. Takeda Ryohei, Yamada Masaki, Tsuruoka Yuko. A case of complication after pre-operative India ink tattooing in a colonic lesion, showed free air in abdominal cavity. Prog. Dig. Endosc. 2009;74:106–107.
1. Singh S., Arif A., Fox C., Basnyat P. Complication after pre-operative India ink tattooing in a colonic lesion. Dig. Surg. 2006;23(303) - PubMed
1. Bang Chang Seok, Kim Yeon Soo, Baik Gwang Ho, Han Sang Hak. Colonic abscess induced by India ink tattooing. Korean J. Gastroenterol. 2014;64:45–48. - PubMed
1. Agha R.A., Borrelli M.R., Farwana R., Koshy K., Fowler A., Orgill D.P., For the SCARE Group The SCARE Statement: updating consensus surgical CAse REport (SCARE) guidelines. Int. J. Surg. 2018;60:132–136. - PubMed

LinkOut - more resources

Full Text Sources

[1] Ishihara Soichieo, Kawai Kazushige, Hata Keisuke. Colonoscopy for surgical treatment of colorectal cancer. Gastroenterol. Endosc. 2016;28:1992–1998.

[2] Ishihara Soichieo, Kawai Kazushige, Hata Keisuke. Colonoscopy for surgical treatment of colorectal cancer. Gastroenterol. Endosc. 2016;28:1992–1998.

[3] Takeda Ryohei, Yamada Masaki, Tsuruoka Yuko. A case of complication after pre-operative India ink tattooing in a colonic lesion, showed free air in abdominal cavity. Prog. Dig. Endosc. 2009;74:106–107.

[4] Takeda Ryohei, Yamada Masaki, Tsuruoka Yuko. A case of complication after pre-operative India ink tattooing in a colonic lesion, showed free air in abdominal cavity. Prog. Dig. Endosc. 2009;74:106–107.

[5] Singh S., Arif A., Fox C., Basnyat P. Complication after pre-operative India ink tattooing in a colonic lesion. Dig. Surg. 2006;23(303) - PubMed

[6] Singh S., Arif A., Fox C., Basnyat P. Complication after pre-operative India ink tattooing in a colonic lesion. Dig. Surg. 2006;23(303) - PubMed

[7] Bang Chang Seok, Kim Yeon Soo, Baik Gwang Ho, Han Sang Hak. Colonic abscess induced by India ink tattooing. Korean J. Gastroenterol. 2014;64:45–48. - PubMed

[8] Bang Chang Seok, Kim Yeon Soo, Baik Gwang Ho, Han Sang Hak. Colonic abscess induced by India ink tattooing. Korean J. Gastroenterol. 2014;64:45–48. - PubMed

[9] Agha R.A., Borrelli M.R., Farwana R., Koshy K., Fowler A., Orgill D.P., For the SCARE Group The SCARE Statement: updating consensus surgical CAse REport (SCARE) guidelines. Int. J. Surg. 2018;60:132–136. - PubMed

[10] Agha R.A., Borrelli M.R., Farwana R., Koshy K., Fowler A., Orgill D.P., For the SCARE Group The SCARE Statement: updating consensus surgical CAse REport (SCARE) guidelines. Int. J. Surg. 2018;60:132–136. - PubMed

Save citation to file

Email citation

Add to Collections

Add to My Bibliography

Your saved search

Create a file for external citation management software

Your RSS Feed

A novel fluorescent marking clip for laparoscopic surgery of colorectal cancer: A case report

Affiliations

A novel fluorescent marking clip for laparoscopic surgery of colorectal cancer: A case report

Authors

Affiliations

Abstract

Figures

Similar articles

Cited by

References

LinkOut - more resources

Full Text Sources

Abstract

Figures

Similar articles

Cited by

References

Related information

LinkOut - more resources

Full Text Sources