Adrenal Venous Sampling: Where Do We Stand?

Endocrinol Metab Clin North Am. 2019 Dec;48(4):843-858. doi: 10.1016/j.ecl.2019.08.012. Epub 2019 Sep 25.


Adrenal venous sampling is the gold standard test to identify surgically curable primary aldosteronism, but it is markedly underused in clinical practice being perceived as a technically challenging and invasive procedure and, moreover, as difficult to interpret. This review provides updated information on current indications to adrenal venous sampling and how to perform and interpret adrenal venous sampling.

Keywords: Adrenal vein sampling; Aldosterone; Diagnosis; Hyperaldosteronism.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adrenal Glands* / blood supply
  • Adrenal Glands* / metabolism
  • Adrenalectomy* / methods
  • Adrenalectomy* / standards
  • Aldosterone / blood*
  • Blood Chemical Analysis* / methods
  • Blood Chemical Analysis* / standards
  • Humans
  • Hyperaldosteronism / blood*
  • Hyperaldosteronism / diagnosis*
  • Procedures and Techniques Utilization* / standards
  • Veins*


  • Aldosterone