The role of anticholinergic medication in the prevention of bradycardia during laparoscopic gynaecological surgery

Aust N Z J Obstet Gynaecol. 2019 Dec;59(6):777-780. doi: 10.1111/ajo.13079. Epub 2019 Oct 27.

Abstract

Bradycardia and cardiac arrest are recognised complications of laparoscopic gynaecological surgery. Anticholinergic agents are indicated in the treatment of perioperative bradyarrhythmia; however, their role in the prevention of bradycardia as a result of insufflation of the peritoneum is less well defined. This article systematically reviewed the literature with respect to the role of anticholinergic agents in the prevention of clinically significant bradyarrhythmia during laparoscopic gynaecological surgery. Eight studies were included for review following an extensive database search. This review highlights the paucity of evidence supporting the prophylactic use of anticholinergic agents in preventing clinically significant bradycardia in women undergoing laparoscopic gynaecological surgery.

Keywords: anticholinergic; bradycardia; laparoscopic gynaecological surgery; pneumoperitoneum.

Publication types

  • Systematic Review

MeSH terms

  • Bradycardia / etiology
  • Bradycardia / prevention & control*
  • Cholinergic Antagonists / therapeutic use*
  • Female
  • Gynecologic Surgical Procedures / adverse effects*
  • Humans
  • Intraoperative Complications / etiology
  • Intraoperative Complications / prevention & control*
  • Laparoscopy / adverse effects*

Substances

  • Cholinergic Antagonists