Triglycerides-to-HDLC Ratio as a Marker of Cardiac Disease and Vascular Risk Factors in Adults

J Coll Physicians Surg Pak. 2019 Nov;29(11):1034-1037. doi: 10.29271/jcpsp.2019.11.1034.


Objective: To find out correlation of triglycerides-to-HDL cholesterol ratio in elders with cardiac risk factors like obesity, diabetes, and hypertension.

Study design: Observational cross-sectional study.

Place and duration of study: Department of Chemical Pathology and Endocrinology, Combined Military Hospital, Rawalpindi, from January to June 2018.

Methodology: Inclusion standards were participants aged 20-59 years .Patients with comorbidity and chronic illness were excluded from the study. A planned standardised homogeneous survey was conducted as a pilot study. Social, economic and physical variables like age, gender, marital status and presence of diseases, all were taken into consideration. To check association among cardio metabolic risk factors like diabetes, obesity, hypertension, and TG/HDL-C ratio, Chi-square test was computed for all cardio metabolic risk factors.

Results: Overall 350 participants were studied after attainment of authorisation from Ethical Review Board of Combined Military Hospital, Rawalpindi, in which 268 (76.6%) were women; whereas, 82 (23.4%) were men with mean age of 37 ± 11.64 years. There was strong association of TG/HDL ratio with BMI, HOMA-IR, WBISI, visceral fats, smooth muscle mass, HDL, LDL, and triglycerides with p <0.04, p <0.001, p <0.01, and p <0.001, respectively.

Conclusion: TG/HDLC ratio can be considered as a potential biomarker for the early prediction of cardiometablic risk factors.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Biomarkers / blood
  • Cardiovascular Diseases / blood*
  • Cholesterol, HDL / blood*
  • Cross-Sectional Studies
  • Diabetes Mellitus / blood
  • Female
  • Humans
  • Hypertension / blood
  • Male
  • Middle Aged
  • Obesity / blood
  • Predictive Value of Tests
  • Risk Factors
  • Triglycerides / blood*


  • Biomarkers
  • Cholesterol, HDL
  • Triglycerides