Pathogen-Negative Sepsis-An Opportunity for Antimicrobial Stewardship

Open Forum Infect Dis. 2019 Oct 9;6(10):ofz397. doi: 10.1093/ofid/ofz397. eCollection 2019 Oct.

Abstract

Sepsis is a common reason for empiric antibiotics among hospitalized patients. We found that the median duration of empiric antibiotics (interquartile range) was 6 (4-9) days among 1047 survivivors with pathogen-negative sepsis. These findings suggest that patients with pathogen-negative sepsis could represent an important opportunity for antimicrobial stewardship.

Keywords: pathogen-negative; sepsis; stewardship.