The PATRIC Bioinformatics Resource Center: expanding data and analysis capabilities

Nucleic Acids Res. 2020 Jan 8;48(D1):D606-D612. doi: 10.1093/nar/gkz943.


The PathoSystems Resource Integration Center (PATRIC) is the bacterial Bioinformatics Resource Center funded by the National Institute of Allergy and Infectious Diseases ( PATRIC supports bioinformatic analyses of all bacteria with a special emphasis on pathogens, offering a rich comparative analysis environment that provides users with access to over 250 000 uniformly annotated and publicly available genomes with curated metadata. PATRIC offers web-based visualization and comparative analysis tools, a private workspace in which users can analyze their own data in the context of the public collections, services that streamline complex bioinformatic workflows and command-line tools for bulk data analysis. Over the past several years, as genomic and other omics-related experiments have become more cost-effective and widespread, we have observed considerable growth in the usage of and demand for easy-to-use, publicly available bioinformatic tools and services. Here we report the recent updates to the PATRIC resource, including new web-based comparative analysis tools, eight new services and the release of a command-line interface to access, query and analyze data.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Algorithms
  • Animals
  • Bacteria / genetics*
  • Caenorhabditis elegans / genetics
  • Chickens / genetics
  • Computational Biology / methods*
  • Databases, Genetic*
  • Drosophila melanogaster / genetics
  • Host-Pathogen Interactions / genetics
  • Humans
  • Internet
  • Macaca mulatta / genetics
  • Metagenomics
  • Mice
  • National Institute of Allergy and Infectious Diseases (U.S.)
  • Phenotype
  • Phylogeny
  • Rats
  • Swine / genetics
  • United States
  • Zebrafish / genetics