Vascular complications in pediatric craniopharyngioma patients: a case-based update

Childs Nerv Syst. 2019 Dec;35(12):2273-2278. doi: 10.1007/s00381-019-04394-8. Epub 2019 Oct 30.

Abstract

Purpose: Craniopharyngiomas remain a challenging entity for neurosurgeons because of their deep-seated, midline location, and intimate relationship with critical neurovascular structures. With high long-term survival rates, patients with craniopharyngioma are likely to experience significant late morbidity related to both disease and therapy.

Method and results: In this paper, we present two cases of late vascular complications after multi-modal treatment of craniopharyngioma.

Conclusion: Available data suggests that pediatric patients with craniopharyngioma represent a particularly vulnerable group.

Keywords: Craniopharyngioma; Fusiform aneurysm; Moyamoya; Postradiational vasculopathy; Vascular injury.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Cerebral Infarction / etiology*
  • Child
  • Child, Preschool
  • Combined Modality Therapy / adverse effects*
  • Combined Modality Therapy / methods
  • Craniopharyngioma / therapy*
  • Female
  • Humans
  • Immunologic Factors / adverse effects
  • Interferon-alpha / therapeutic use
  • Intracranial Aneurysm / etiology*
  • Neoplasm Recurrence, Local / therapy
  • Neurosurgical Procedures / adverse effects
  • Neurosurgical Procedures / methods
  • Pituitary Neoplasms / therapy*
  • Postoperative Complications / etiology
  • Proton Therapy / adverse effects
  • Proton Therapy / methods
  • Radiosurgery / adverse effects
  • Radiosurgery / methods

Substances

  • Immunologic Factors
  • Interferon-alpha