Abstract
Purpose:
Craniopharyngiomas remain a challenging entity for neurosurgeons because of their deep-seated, midline location, and intimate relationship with critical neurovascular structures. With high long-term survival rates, patients with craniopharyngioma are likely to experience significant late morbidity related to both disease and therapy.
Method and results:
In this paper, we present two cases of late vascular complications after multi-modal treatment of craniopharyngioma.
Conclusion:
Available data suggests that pediatric patients with craniopharyngioma represent a particularly vulnerable group.
Keywords:
Craniopharyngioma; Fusiform aneurysm; Moyamoya; Postradiational vasculopathy; Vascular injury.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Cerebral Infarction / etiology*
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Child
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Child, Preschool
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Combined Modality Therapy / adverse effects*
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Combined Modality Therapy / methods
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Craniopharyngioma / therapy*
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Female
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Humans
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Immunologic Factors / adverse effects
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Interferon-alpha / therapeutic use
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Intracranial Aneurysm / etiology*
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Neoplasm Recurrence, Local / therapy
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Neurosurgical Procedures / adverse effects
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Neurosurgical Procedures / methods
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Pituitary Neoplasms / therapy*
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Postoperative Complications / etiology
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Proton Therapy / adverse effects
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Proton Therapy / methods
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Radiosurgery / adverse effects
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Radiosurgery / methods
Substances
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Immunologic Factors
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Interferon-alpha