Progressive Maculopathy After Discontinuation of Pentosan Polysulfate Sodium

Ophthalmic Surg Lasers Imaging Retina. 2019 Oct 1;50(10):656-659. doi: 10.3928/23258160-20191009-10.


A pigmentary maculopathy associated with chronic use of the drug pentosan polysulfate sodium (PPS) was recently described. The authors present a case of PPS-associated maculopathy that continued to progress for 6 years after discontinuation of this medication. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:656-659.].

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anticoagulants / adverse effects*
  • Disease Progression
  • Female
  • Humans
  • Macular Degeneration / chemically induced*
  • Middle Aged
  • Pentosan Sulfuric Polyester / adverse effects*


  • Anticoagulants
  • Pentosan Sulfuric Polyester