Parathyroid Pathology

Surg Pathol Clin. 2019 Dec;12(4):1007-1019. doi: 10.1016/j.path.2019.08.006. Epub 2019 Sep 27.


Proliferative pathologic lesions of parathyroid glands encompass a spectrum of entities ranging from benign hyperplastic processes to malignant neoplasia. This review article outlines the pathophysiologic classification of parathyroid disorders and describes histologic, immunohistochemical, and molecular features that can be assessed to render accurate diagnoses.

Keywords: Parafibromin; Parathyroid; Parathyroid adenoma; Parathyroid carcinoma; Primary hyperplasia.

Publication types

  • Review

MeSH terms

  • Adenoma / pathology*
  • Humans
  • Hyperparathyroidism / pathology*
  • Immunohistochemistry
  • Parathyroid Glands / anatomy & histology
  • Parathyroid Glands / embryology
  • Parathyroid Glands / pathology*
  • Parathyroid Neoplasms / pathology*