Mechanisms of Probiotic Action in the Honeybee

Crit Rev Eukaryot Gene Expr. 2019;29(2):95-103. doi: 10.1615/CritRevEukaryotGeneExpr.2019025358.


As the beekeeping industry develops, increases in honey yield is dependent on colony health. The honeybee gut bacteria originate from their natural habitat and food, nectar, pollen, and water intake. Extensive studies have been carried out to determine specific suitable probiotic bacteria for honeybees. The main goal of this research is to control diseases, not increase honey production; however, a healthier colony will certainly produce more honey. It has been shown that lactic acid bacteria isolated from honeybees has beneficial effects on bee health and reduces the prevalence of pathogens. Adding a mixture of Lactobacillus to the feed of larvae leads to a reduction in infection. Knowledge of molecular mechanisms of probiotics in protecting honeybee colonies against pathogens is important.

MeSH terms

  • Animal Feed / microbiology
  • Animals
  • Bees / microbiology*
  • Gastrointestinal Tract / microbiology
  • Lactobacillus / physiology*
  • Larva / microbiology
  • Probiotics*