Making HIS mice more human-like

John A Simpson; Matthew E Brown

doi:10.1002/JLB.5CE1019-262R

Making HIS mice more human-like

J Leukoc Biol. 2020 Jan;107(1):9-10. doi: 10.1002/JLB.5CE1019-262R. Epub 2019 Nov 4.

Authors

John A Simpson¹, Matthew E Brown¹

Affiliation

¹ University of Wisconsin-Madison, Madison, WI, USA.

PMID: 31682279
DOI: 10.1002/JLB.5CE1019-262R

Abstract

Discussion on exhaustion/senescence marker profiles on human T cells in BRGSF-A2 humanized mice and how they resemble those in human samples; describes how this model fits into the humanized-mouse research field.

Publication types

Editorial
Comment

MeSH terms

Animals
Biomarkers
Humans
Mice
T-Lymphocytes*

Substances

Biomarkers