Different treatment protocols for moderate idiopathic sudden sensorineural hearing loss

Undersea Hyperb Med. 2019;46(5):659-663.

Abstract

Treatment of idiopathic sensorineural hearing loss (ISSNHL) is problematic due to the unclear etiology of the illness. Corticosteroid is recommended by some papers, and hyperbaric oxygen (HBO2) by others. Recently HBO2 has been shown to be an important therapy for ISSNHL, with an increasing number of studies demonstrating its beneficial results. Recovery from ISSNHL depends on the interval period between onset and treatment, hearing loss severity and audiogram type used to determine damage. Treatment of ISSNHL requires a detailed analysis. In this retrospective study we reviewed data from 56 patients with moderate ISSNHL. These patients were divided into three groups based on different treatments: corticosteroid group; corticosteroid + HBO2 (combination)group; and HBO2-only group. Additionally, all patients received intravenous vasodilator treatment. Hearing levels before and after treatment were compared. All three groups had a similar recovery rate, with an effective rate of more than 50%, and a hearing gain average of 17.38 decibels (dB). HBO2 treatment got a higher recovery rate. The combination therapy, which included corticosteroid and HBO2, did not elevate the recovery rate.

Keywords: corticosteroid; hyperbaric oxygen therapy; sensorineural hearing loss.

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use*
  • Combined Modality Therapy / methods
  • Female
  • Hearing Loss, Sensorineural / therapy*
  • Hearing Loss, Sudden / therapy*
  • Humans
  • Hyperbaric Oxygenation*
  • Injections, Intravenous
  • Male
  • Middle Aged
  • Prednisone / administration & dosage
  • Recovery of Function
  • Retrospective Studies
  • Vasodilator Agents / administration & dosage*

Substances

  • Adrenal Cortex Hormones
  • Vasodilator Agents
  • Prednisone