A Case of Histiocytic Sarcoma Arising from Mycosis Fungoides

Ethan A Burns; Cesar Gentille; Saro Kasparian; Sai Ravi Pingali

doi:10.1155/2019/7834728

A Case of Histiocytic Sarcoma Arising from Mycosis Fungoides

Case Rep Hematol. 2019 Oct 3:2019:7834728. doi: 10.1155/2019/7834728. eCollection 2019.

Authors

Ethan A Burns¹, Cesar Gentille², Saro Kasparian¹, Sai Ravi Pingali²

Affiliations

¹ Houston Methodist Hospital, Department of Medicine, 6550 Fannin St, Ste 1101, Houston, TX 77030, USA.
² Houston Methodist Cancer Center, 6445 Main St Floor 24, Houston, TX 77030, USA.

Abstract

Histiocytic sarcoma (HS) is an uncommon malignant neoplasm arising from mature histiocytes and most commonly characterized by the immunophenotypic expression of CD68, CD163, or lysozyme. Although rare, HS arising as a second primary malignancy following hematolymphoid neoplasms has been reported. To our knowledge, this is the first reported case of HS occurring as a second primary malignancy in a patient with mycosis fungoides (MF), with the retained immunophenotype markers CD30 and CD4.

Publication types

Case Reports