Background: Hyaluronic acid fillers have a satisfactory safety profile. However, adverse reactions do occur, and rarely intravascular injection may lead to blindness. Currently there is no internationally recognized consensus on the prevention or management of blindness from hyaluronic acid filler.
Objectives: The authors sought to give guidance on how to minimize the risk and optimize the management of this rare but catastrophic adverse reaction.
Methods: A multinational group of experts in cosmetic injectables from multiple disciplines convened to review current best practice and develop updated consensus recommendations for prevention and bedside intervention if visual loss occurs after cosmetic injection of hyaluronic acid filler.
Results: The consensus group provided specific recommendations focusing on the consenting process, prevention, and early management of visual impairment related to intravascular hyaluronic acid filler injection.
Conclusions: Although visual loss due to filler injections is rare, it is important that both patient and physician be aware of this risk. In this paper the authors describe methods and techniques available to reduce the risk and also document suggested initial management should a clinician find themselves in this situation.
背景: 透明質酸填充劑具有令人滿意的安全性。但是，確實會發生不良反應，很少進行血管內註射可能導致失明。當前，關於透明質酸填充劑的失明的預防或管理尚無國際公認的共識。
目標: 作者試圖就如何減少這種罕見但災難性的不良反應的風險和優化管理提供指導。
方法: 來自多個學科的化妝品注射劑國際專家小組召集起來，審查當前的最佳實踐，並為透明質酸填充劑化妝品注射後出現視力下降提出預防和床旁干預的最新共識建議。
結果: 共識小組提供了針對與血管內透明質酸填充劑注射相關的視覺障礙的同意過程，預防和早期治療的具體建議。
結論: 儘管很少發生因填充劑注射引起的視力喪失，但重要的是患者和醫師都應注意這種風險。在本文中，作者描述了可用於降低風險的方法和技術，還提出了建議，如果臨床醫生髮現自己處於這種情況，則應進行初步治療。
© 2019 The Aesthetic Society.