Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Ceramides

doi:10.1056/NEJMcibr1910023

Comment

. 2019 Nov 7;381(19):1866-1869.

doi: 10.1056/NEJMcibr1910023.

Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Ceramides

Varman T Samuel¹, Gerald I Shulman¹

Affiliations

Affiliation

¹ From the Departments of Internal Medicine (V.T.S., G.I.S.) and Cellular and Molecular Physiology (G.I.S.), Yale School of Medicine, New Haven, and the Veterans Affairs Medical Center, West Haven (V.T.S.) - both in Connecticut.

PMID: 31693811
DOI: 10.1056/NEJMcibr1910023

Comment

Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Ceramides

Varman T Samuel et al. N Engl J Med. 2019.

. 2019 Nov 7;381(19):1866-1869.

doi: 10.1056/NEJMcibr1910023.

Authors

Varman T Samuel¹, Gerald I Shulman¹

Affiliation

¹ From the Departments of Internal Medicine (V.T.S., G.I.S.) and Cellular and Molecular Physiology (G.I.S.), Yale School of Medicine, New Haven, and the Veterans Affairs Medical Center, West Haven (V.T.S.) - both in Connecticut.

PMID: 31693811
DOI: 10.1056/NEJMcibr1910023

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Targeting a ceramide double bond improves insulin resistance and hepatic steatosis.
Chaurasia B, Tippetts TS, Mayoral Monibas R, Liu J, Li Y, Wang L, Wilkerson JL, Sweeney CR, Pereira RF, Sumida DH, Maschek JA, Cox JE, Kaddai V, Lancaster GI, Siddique MM, Poss A, Pearson M, Satapati S, Zhou H, McLaren DG, Previs SF, Chen Y, Qian Y, Petrov A, Wu M, Shen X, Yao J, Nunes CN, Howard AD, Wang L, Erion MD, Rutter J, Holland WL, Kelley DE, Summers SA. Chaurasia B, et al. Science. 2019 Jul 26;365(6451):386-392. doi: 10.1126/science.aav3722. Epub 2019 Jul 4. Science. 2019. PMID: 31273070 Free PMC article.

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Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Ceramides

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Nonalcoholic Fatty Liver Disease, Insulin Resistance, and Ceramides

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