Objective: To explore whether exercise could influence outcomes and improve life quality of patients with knee osteoarthritis. Methods: This study included 210 patients diagnosed with knee osteoarthritis from October to December 2018 in Shijiazhuang Derui Exercise Rehabilitation Medical Center. These patients were divided into two groups with random number table: experiment and control group. Patients in experimental group got exercise rehabilitation training and routine therapy,but patients in control group got routine treatment only that included physical therapy and non-steroidal anti-inflammatory drugs (NSAIDs). We applied different kinds of measure to follow-up these patients,which included Lysholm scale, the Western Ontario and McMaster Osteoarthritis Index (WOMAC), SF-36 life quality questionnaire, and knee range of motion.The degree of pain and symptoms and the knee function and the quality of life in the two groups were recorded too. Paired sample t test was used to compare the data between the two groups. Results: There were 105 patients in each group, but 13 cases (12.4%) in experimental group and 6 patients (5.7%) in control group were lost,respectively.All the patients were followed up for (12.0±2.3) weeks. There was no significant differences in age, body mass index, gender between the two groups. At the final follow-up, the WOMAC score in the experiment group was 84.4±6.8, and it was 108.3±1.7 in the control group (t=-4.71, P<0.05);the Lysholm score of the experimental group was 65.5±4.7, and it was 41.2±1.4 in the control group (t=7.29, P<0.05); the knee range of motion in the experiment group and control group was 121°±7° and 114°±3°, respectively (t=1.83, P<0.05); the SF-36 score in the two groups was 90.0±2.8 and 75.6±1.5, respectively (t=6.15, P<0.05). Conclusion: Exercise rehabilitation plus routine therapy for patients with knee osteoarthritis can effectively improve outcome, promote functional recovery and improve quality of life.
目的： 研究膝骨关节炎（KOA）患者进行运动康复训练对预后的影响。 方法： 将2018年10月至2018年12月在石家庄德瑞运动康复医疗中心诊断为膝关节炎的210例患者通过使用随机数字表进行分组，试验组进行运动康复训练加常规治疗，对照组单独进行常规保守治疗（物理治疗和服用非甾体类抗炎药物）。在入组时和随访期末应用Lysholm评分问卷、西安大略和麦柯玛斯特大学骨关节炎指数量表（WOMAC）、SF-36生活质量评价表及膝关节功能检查综合评估，比较两组患者疼痛的改善程度、症状及膝关节功能恢复和生活质量方面的差异。组间数据比较采用配对样本t检验。 结果： 本项研究共纳入KOA患者210例，其中试验组纳入105例，失访13例（12.4%）；对照组纳入105例，失访6例（5.7%）。全组患者平均随访（12.0±2.3）周。两组患者在年龄、体质指数、性别等差异均无统计学意义。末次随访时，试验组WOMAC评分为（84.4±6.8）分，对照组为（108.3±1.7）分（t=-4.71，P<0.05）；试验组Lysholm评分为（65.5±4.7）分，对照组为（41.2±1.4）分（t=7.29，P<0.05）；试验组膝关节活动度为121°±7°，对照组为114°±3°（t=1.83，P<0.05）；试验组SF-36评分为（90.0±2.8）分，对照组为（75.6±1.5）分（t=6.15，P<0.05）。 结论： 运动康复训练可有效改善患者症状和疼痛程度，有助于提高患者的生活质量。.
Keywords: Knee osteoarthritis; Randomized controlled trial; Rehabilitation exercise.