Blood monitoring of circulating tumor plasma cells by next generation flow in multiple myeloma after therapy

Luzalba Sanoja-Flores; Juan Flores-Montero; Noemi Puig; Teresa Contreras-Sanfeliciano; Roberia Pontes; Alba Corral-Mateos; Omar García-Sánchez; María Díez-Campelo; Roberto José Pessoa de Magalhães; Luis García-Martín; José María Alonso-Alonso; Aranzazú García-Mateo; Carlos Aguilar-Franco; Jorge Labrador; Abelardo Barez-García; Angelo Maiolino; Bruno Paiva; Jesús San Miguel; Elaine Sobral da Costa; Marcos González; María Victoria Mateos; Brian Durie; Jacques J M van Dongen; Alberto Orfao

doi:10.1182/blood.2019002610

Blood monitoring of circulating tumor plasma cells by next generation flow in multiple myeloma after therapy

Blood. 2019 Dec 12;134(24):2218-2222. doi: 10.1182/blood.2019002610.

Authors

Luzalba Sanoja-Flores^{1

2

3

4

5}, Juan Flores-Montero^{1

2

3

4

5}, Noemi Puig^{1

4

5

6}, Teresa Contreras-Sanfeliciano⁷, Roberia Pontes⁸, Alba Corral-Mateos^{1

2

3

4

5}, Omar García-Sánchez^{1

4

5

6}, María Díez-Campelo^{1

4

5

6}, Roberto José Pessoa de Magalhães⁹, Luis García-Martín¹⁰, José María Alonso-Alonso¹¹, Aranzazú García-Mateo¹², Carlos Aguilar-Franco¹³, Jorge Labrador¹⁴, Abelardo Barez-García¹⁵, Angelo Maiolino⁹, Bruno Paiva^{4

16}, Jesús San Miguel^{4

16}, Elaine Sobral da Costa⁸, Marcos González^{1

4

5

6}, María Victoria Mateos^{1

4

5

6}, Brian Durie¹⁷, Jacques J M van Dongen¹⁸, Alberto Orfao^{1

2

3

4

5}

Affiliations

¹ Cancer Research Center-Instituto de Biología Celular y Molecular del Cáncer (IBMCC) of the Consejo Superior de Investigaciones Científicas (CSIC) and University of Salamanca (USAL), Salamanca, Spain.
² Cytometry Service (NUCLEUS) and.
³ Department of Medicine, University of Salamanca, Salamanca, Spain.
⁴ Centro de Investigación Biomédica en Red de Cáncer (CIBER-ONC), Instituto Carlos III, Madrid, Spain.
⁵ Instituto de Investigación Biosanitaria (IBSAL), Salamanca, Spain.
⁶ Department of Hematology and.
⁷ Department of Biochemistry, University Hospital of Salamanca, Salamanca, Spain.
⁸ Department of Pediatrics, Institute of Pediatrics and Puericulture Martagão Gesteira (IPPMG) and.
⁹ University Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.
¹⁰ Department of Hematology, Hospital of Zamora, Zamora, Spain.
¹¹ Department of Hematology, Hospital of Palencia, Palencia, Spain.
¹² Department of Hematology, Hospital of Segovia, Segovia, Spain.
¹³ Department of Hematology, Hospital of Soria, Soria, Spain.
¹⁴ Department of Hematology, Hospital of Burgos, Burgos, Spain.
¹⁵ Department of Hematology, Hospital of Ávila, Ávila, Spain.
¹⁶ Clinica Universidad de Navarra, Applied Medical Research Center (CIMA), IDISNA, Pamplona, Spain.
¹⁷ Cedars-Sinai Samuel Oschin Cancer Center, Los Angeles, CA; and.
¹⁸ Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Flow Cytometry* / methods
Humans
Immunophenotyping* / methods
Multiple Myeloma / diagnosis*
Multiple Myeloma / metabolism*
Multiple Myeloma / mortality
Multiple Myeloma / therapy
Neoplastic Cells, Circulating / metabolism*
Neoplastic Cells, Circulating / pathology
Plasma Cells / metabolism*
Plasma Cells / pathology
Prognosis