Wedging open a catalytic site

Elife. 2019 Nov 8;8:e52418. doi: 10.7554/eLife.52418.


The activation mechanism of the nitric oxide receptor has been revealed by cryo-electron microscopy.

Keywords: CryoEM; allostery; biochemistry; chemical biology; cyclic GMP; manduca sexta; nitric oxide; none.

Publication types

  • Comment

MeSH terms

  • Animals
  • Catalytic Domain
  • Cryoelectron Microscopy
  • Cyclic GMP*
  • Manduca*
  • Nitric Oxide
  • Soluble Guanylyl Cyclase


  • Nitric Oxide
  • Soluble Guanylyl Cyclase
  • Cyclic GMP