Spontaneous systemic hypertension in dogs: five cases (1981-1983)

J Am Vet Med Assoc. 1988 Aug 15;193(4):486-94.


Spontaneous (not experimentally induced) systemic hypertension was detected in 5 male dogs that were examined because of apparent blindness caused by intraocular hemorrhage and/or retinal detachment. Secondary causes of hypertension, including renal, adrenal, and thyroid disease, were investigated. Four of the dogs had glomerulonephropathy, renal insufficiency, and proteinuria. Four dogs had compensatory cardiac hypertrophy. Hypertension in 4 of 5 dogs was associated with glomerulosclerosis with chronic renal insufficiency, bilateral adrenocortical hyperplasia, adrenocortical adenoma with renal amyloidosis, and immune-mediated glomerulonephritis with chronic renal insufficiency, respectively. The fifth dog was determined to have essential hypertension. The dogs were treated for their primary diseases. Sodium restriction alone was inadequate to reduce blood pressure; 4 of the dogs also required antihypertensive medications.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Blindness / etiology
  • Blindness / veterinary*
  • Dog Diseases / diagnosis*
  • Dog Diseases / etiology
  • Dog Diseases / pathology
  • Dogs
  • Eye Hemorrhage / complications
  • Eye Hemorrhage / veterinary*
  • Hypertension / diagnosis
  • Hypertension / etiology
  • Hypertension / veterinary*
  • Hypertension, Renal / pathology
  • Hypertension, Renal / veterinary
  • Male
  • Retinal Detachment / complications
  • Retinal Detachment / veterinary*