Aim: The aim of this study is to evaluate the remineralization potential of Clinpro XT varnish containing tricalcium phosphate (TCP) and MI varnish containing casein phosphopeptide (casein phosphopeptide-amorphous calcium phosphate, CPP-ACP).
Materials and methods: Thirty premolar teeth were taken and divided into three groups. Samples were sliced mesiodistally into buccal and lingual halves using a diamond disk bur. The buccal halves of the teeth were used for the study. Artificial caries like lesions were produced and evaluated with Diagnodent. The samples in each group were treated with the respective remineralizing agent (except for the control group) at every 24 hours for 7 days and the surfaces were assessed using Diagnodent to record the values after the remineralization procedure. The Diagnodent values obtained were tabulated and statistically analyzed using one-way ANOVA and Tukey's multiple comparison tests.
Results: There was a significant difference between the values calculated before and after remineralization in all the three groups.
Conclusion: The study findings showed that MI varnish containing CPP-ACP had the highest release of fluoride as compared to the Clinpro fluoride releasing varnish.
Clinical significance: MI varnish is a 5% NaF varnish containing CPP-ACP to give an exceptional fluoride varnish that releases more bioavailable fluoride, calcium, and phosphate, hence, can be used successfully in remineralization of early carious lesions. CPP-ACP can be used in the clinical practice for reversing or arresting the early carious lesions.
How to cite this article: Varma V, Hegde KS, et al. Comparative Evaluation of Remineralization Potential of Two Varnishes Containing CPP-ACP and Tricalcium Phosphate: An In Vitro Study. Int J Clin Pediatr Dent 2019;12(3):233-236.
Keywords: Clinpro varnish; MI varnish with CPP–ACP; Tooth remineralization.
Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.
Conflict of interest statement
Source of support: Nil Conflict of interest: None
Comparative Evaluation of Remineralization Potential of Casein Phosphopeptide-Amorphous Calcium Phosphate and Casein Phosphopeptide-Amorphous Calcium Phosphate Fluoride on Artificial Enamel White Spot Lesion: An in Vitro Light Fluorescence StudyR Mehta et al. Indian J Dent Res 24 (6), 681-9. PMID 24552927.
As compared with artificial saliva both CPP-ACP and CPP-ACFP produced significant amount of remineralization of the artificial enamel white spot lesion (P < 0.001), ho…
An in Vitro Comparative Evaluation of Three Remineralizing Agents Using Confocal MicroscopyK Chokshi et al. J Clin Diagn Res 10 (6), ZC39-42. PMID 27504408.Fluoride varnish showed the greatest remineralization potential of artificial carious lesions followed by CPP-ACP Paste and fTCP Paste respectively.
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Anticariogenicity of Casein Phosphopeptide-Amorphous Calcium Phosphate: A Review of the LiteratureC Llena et al. J Contemp Dent Pract 10 (3), 1-9. PMID 19430620. - ReviewRemineralization of white spot lesions has been achieved clinically by applying pastes based on these compounds, and a similar effect to self-applied fluorides has been o …
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