Anti-inflammatory effects of Rhodiola rosea L.: A review

Biomed Pharmacother. 2020 Jan;121:109552. doi: 10.1016/j.biopha.2019.109552. Epub 2019 Nov 9.


Rhodiola rosea L., a worldwide botanical adaptogen, has been confirmed to possess protective effects of inflammatory injury for many diseases, including cardiovascular diseases, neurodegenerative diseases, diabetes, sepsis, and cancer. This paper is to review the recent clinical and experimental researches about the anti-inflammatory effects and the related mechanisms of Rhodiola rosea L. extracts, preparations, and the active compounds. From the collected information reviewed, this paper will provide the theoretical basis for its clinical application, and provide the evidences or guidance for future studies and medicinal exploitations of Rhodiola rosea L.

Keywords: Anti-Inflammation; Rhodiola rosea L.; Salidroside; Sofren injection.

Publication types

  • Review

MeSH terms

  • Animals
  • Anti-Inflammatory Agents / isolation & purification
  • Anti-Inflammatory Agents / pharmacology*
  • Humans
  • Inflammation / drug therapy
  • Inflammation / pathology
  • Plant Extracts / pharmacology*
  • Rhodiola / chemistry*


  • Anti-Inflammatory Agents
  • Plant Extracts