Auxotrophic heterozygosities and the ploidy of Candida parapsilosis and Candida krusei

J Med Vet Mycol. 1988 Jun;26(3):163-71.


Evidence is presented that the type strain of Candida parapsilosis, ATCC 22019, is heterozygous MET/met and that Candida krusei Y 10930 is heterozygous URA/ura. This URA gene determines orotidine-5'-phosphate decarboxylase activity. Because each of these strains is demonstrably disomic for at least one chromosome, they are not haploid but must be diploid or aneuploid.

MeSH terms

  • Candida / genetics*
  • Candida / metabolism
  • Culture Media
  • Genes, Fungal
  • Genetic Markers
  • Heterozygote*
  • Orotic Acid / metabolism
  • Orotidine-5'-Phosphate Decarboxylase / genetics
  • Ploidies*
  • Ultraviolet Rays


  • Culture Media
  • Genetic Markers
  • Orotic Acid
  • Orotidine-5'-Phosphate Decarboxylase