Coyne's (1976b) interactional theory of the social environment's role in maintaining depression suggests that depressed people create negative affect in others. This leads to a pattern of interactions between depressed individuals and others that is aversive to both parties and becomes a vicious circle. We examined interactions of 15 depressed and 15 nondepressed college students with their roommates. On questionnaires, roommates did indicate more rejection, dislike, and avoidance of the depressed students than of the nondepressed students, consistent with Coyne's theory, and depressed-student-roommate interactions were more personally involved (higher percentage of self-disclosure) and less positive than nondepressed-student-roommate interactions. The moods of both depressed students and their roommates were worse than those of controls before the interaction but, contrary to expectation, improved over the course of the interaction, whereas the moods of nondepressed students and their roommates did not change significantly. Implications of these results for Coyne's theory are discussed.