Dietary Fish Oil Concentrates Associated Health Benefits: A Recent Development of Cardiovascular Risk Reduction

Curr Pharm Des. 2019;25(38):4053-4062. doi: 10.2174/1381612825666191112141320.

Abstract

Fish oil is an abundant source of omega-3 (n-3 or ω-3) polyunsaturated fatty acids (PUFAs) and contains Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA). PUFAs are very effective in preventing/ inhibiting cardiovascular incidents, particularly in individuals with high cardiovascular risk/accidents. In this review, composition, extraction of fish oil and its favorable/beneficial effects in Cardiovascular Diseases (CVDs) and molecular mechanism for its treatment/reduction have been discussed. Moreover, the application of fish oil for preventive/protective and remedial/curative properties in nutritive and health benefits has been summarized. All these aspects further search the opportunities/hope and scope with its expected opening and anticipations/ possibilities to provide additional therapeutic substitutes for the reduction of CVDs and registration of new drugs.

Keywords: Fish oil; cardiovascular disease; molecular mechanism; omega-3; polyunsaturated fatty acid; therapeutic substitutes..

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases / prevention & control*
  • Docosahexaenoic Acids
  • Eicosapentaenoic Acid
  • Fatty Acids, Omega-3 / pharmacology*
  • Fish Oils / pharmacology*
  • Humans
  • Risk Factors

Substances

  • Fatty Acids, Omega-3
  • Fish Oils
  • Docosahexaenoic Acids
  • Eicosapentaenoic Acid