A word of caution against excessive protein intake

Nat Rev Endocrinol. 2020 Jan;16(1):59-66. doi: 10.1038/s41574-019-0274-7. Epub 2019 Nov 14.


Dietary protein is crucial for human health because it provides essential amino acids for protein synthesis. In addition, dietary protein is more satiating than carbohydrate and fat. Accordingly, many people consider the protein content when purchasing food and beverages and report 'trying to eat more protein'. The global market for protein ingredients is projected to reach approximately US$90 billion by 2021, largely driven by the growing demand for protein-fortified food products. This Perspective serves as a caution against the trend of protein-enriched diets and provides an evidence-based counterpoint that underscores the potential adverse public health consequences of high protein intake.

Publication types

  • Review

MeSH terms

  • Dietary Proteins / administration & dosage*
  • Dietary Proteins / adverse effects*
  • Dietary Proteins / metabolism
  • Energy Intake / physiology*
  • Food, Fortified* / adverse effects
  • Humans
  • Prediabetic State / chemically induced
  • Prediabetic State / metabolism
  • Risk Factors


  • Dietary Proteins