Hereford cattle immunized and protected against Boophilus microplus with soluble and membrane-associated antigens from the midgut of ticks

J P Opdebeeck; J Y Wong; L A Jackson; C Dobson

doi:10.1111/j.1365-3024.1988.tb00230.x

Hereford cattle immunized and protected against Boophilus microplus with soluble and membrane-associated antigens from the midgut of ticks

Parasite Immunol. 1988 Jul;10(4):405-10. doi: 10.1111/j.1365-3024.1988.tb00230.x.

Authors

J P Opdebeeck¹, J Y Wong, L A Jackson, C Dobson

Affiliation

¹ Department of Parasitology, University of Queensland, St Lucia, Brisbane, Australia.

PMID: 3174172
DOI: 10.1111/j.1365-3024.1988.tb00230.x

Abstract

Hereford cattle were immunized with membranes and soluble components extracted from the midgut of Boophilus microplus. Membrane vaccines protected cattle (91%) against challenge with 3 x 20,000 larval ticks administered at intervals of 7 days. Vaccines made from soluble antigens did not protect cattle. Antibody levels measured by enzyme-linked immunosorbent assay (ELISA) related to the levels of protection induced by vaccination.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antibody Formation
Antigens / immunology*
Cattle
Cattle Diseases / prevention & control*
Male
Tick Infestations / prevention & control
Tick Infestations / veterinary*
Ticks / immunology*
Vaccination / veterinary*

Substances

Antigens