On the Effectiveness of Deep Representation Learning: the Atrial Fibrillation Case

Computer (Long Beach Calif). 2019 Nov;52(11):18-29. doi: 10.1109/MC.2019.2932716. Epub 2019 Oct 21.

Abstract

The automatic and unsupervised analysis of biomedical time series is of primary importance for diagnostic and preventive medicine, enabling fast and reliable data processing to reveal clinical insights without the need for human intervention. Representation learning (RL) methods perform an automatic extraction of meaningful features that can be used, e.g., for a subsequent classification of the measured data. The goal of this study is to explore and quantify the benefits of RL techniques of varying degrees of complexity, focusing on modern deep learning (DL) architectures. We focus on the automatic classification of atrial fibrillation (AF) events from noisy single-lead electrocardiographic signals (ECG) obtained from wireless sensors. This is an important task as it allows the detection of sub-clinical AF which is hard to diagnose with a short in-clinic 12-lead ECG. The effectiveness of the considered architectures is quantified and discussed in terms of classification performance, memory/data efficiency and computational complexity.