The effect of bilirubin on long-term mortality in patients with chronic total coronary occlusion

Bratisl Lek Listy. 2019;120(11):860-863. doi: 10.4149/BLL_2019_143.

Abstract

Aim: We intended to investigate the association of bilirubin with total mortality in patients with chronic total coronary occlusion (CTO).

Methods: We included 172 patients who underwent coronary angiography due to stable angina pectoris and had CTO. We checked the viability of patients after 9 years of follow-up.

Results: Direct bilirubin levels were significantly lower in the non-viable group. We revealed age (OR = 1.045, 95% C.I: 1.009‒1.083; p = 0.015) and direct bilirubin concentrations (OR = 0.029, 95% C.I: 0.002‒0.435; p = 0.029) as independent predictors of mortality. Direct bilirubin value of > 0.2 mg/dL was associated with decreased mortality with a sensitivity of 85 %, and a specificity of 46 %.

Conclusion: Serum direct bilirubin concentrations independently predict total mortality in patients with chronic total occlusion over 9 years of follow-up (Tab. 1, Fig. 2, Ref. 23).

Keywords: bilirubin; chronic total occlusion long-term mortality..

MeSH terms

  • Bilirubin / blood*
  • Chronic Disease
  • Coronary Angiography
  • Coronary Occlusion / mortality*
  • Humans
  • Risk Factors

Substances

  • Bilirubin