Sleep physiology and disorders in aging and dementia

Handb Clin Neurol. 2019:167:477-493. doi: 10.1016/B978-0-12-804766-8.00026-1.

Abstract

Sleep problems occur commonly in normal and pathologic aging. Older adults typically have more difficulty falling asleep and remaining asleep, report more daytime napping, and have an increased prevalence of primary sleep disorders such as insomnia, parasomnias, sleep apnea, and sleep-related movement disorders. Medical and psychiatric disorders as well as medications used to treat them also contribute to sleep disturbances in aging. Patients with mild cognitive impairment and dementia have more severe sleep problems, and disturbed sleep and sleep disorders contribute to earlier onset and more rapid progression of neurodegenerative disorders. Approaches to diagnosing and treating sleep disorders in the elderly are discussed.

Keywords: Aging; Dementia; Insomnia; Sleep; Sleep apnea; Sleep disorders.

Publication types

  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aging*
  • Dementia / complications*
  • Female
  • Humans
  • Male
  • Sleep Wake Disorders / epidemiology*
  • Sleep Wake Disorders / etiology*
  • Sleep Wake Disorders / therapy*