Multitasking Actors of Staphylococcus aureus Metabolism and Virulence

Trends Microbiol. 2020 Jan;28(1):6-9. doi: 10.1016/j.tim.2019.10.013. Epub 2019 Nov 18.


Recent studies have uncovered the striking commonality of multitasking molecular actors linking metabolism and virulence regulation. Beyond the well known importance of carbohydrate and amino acid metabolism regulators in coordinating metabolic pathways and pathogenesis, we highlight recent major advances linking lipid and nucleic acid pathways to virulence regulation in Staphylococcus aureus.

Keywords: Staphylococcus aureus; metabolism; virulence.

MeSH terms

  • Amino Acids / metabolism
  • Animals
  • Biosynthetic Pathways
  • Carbohydrate Metabolism
  • Fatty Acids / metabolism
  • Humans
  • Metabolic Networks and Pathways
  • Staphylococcal Infections / microbiology*
  • Staphylococcus aureus / metabolism*
  • Staphylococcus aureus / pathogenicity*
  • Virulence


  • Amino Acids
  • Fatty Acids