Hypomagnesaemia in elderly digitalised patients

Scott Med J. 1988 Jun;33(3):273-4. doi: 10.1177/003693308803300309.

Abstract

Hypomagnesaemia and hypokalaemia are known to predispose to digoxin toxicity. Elderly patients receiving diuretics may be at special risk. A 12-month survey of all patients receiving digoxin at the time of admission to our Geriatric Assessment Unit revealed 16% were hypomagnesaemic, whereas no patient was hypokalaemic. There is a need for greater awareness of the risk of magnesium depletion in elderly patients receiving concurrent diuretic and digoxin therapy.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Digoxin / adverse effects*
  • Digoxin / pharmacokinetics
  • Diuretics / adverse effects*
  • Drug Therapy, Combination
  • Humans
  • Magnesium / blood
  • Magnesium Deficiency / blood
  • Magnesium Deficiency / chemically induced*
  • Potassium / blood
  • Sodium / blood

Substances

  • Diuretics
  • Digoxin
  • Sodium
  • Magnesium
  • Potassium