Dawn of a New Era of Targeted Antioxidant Therapies

Cell Chem Biol. 2019 Nov 21;26(11):1483-1485. doi: 10.1016/j.chembiol.2019.11.003.

Abstract

In this issue of Cell Chemical Biology, Shah et al. (2019) report an in vitro, high-throughput assay that predicts the ability of compounds to suppress peroxidation of phospholipids. This approach provides a way to design and optimize targeted antioxidants that suppress specific oxidative event in cells, potentially overcoming previous failures with generic antioxidants.

Publication types

  • Comment

MeSH terms

  • Antioxidants*
  • Cell Death
  • Fluorescence
  • Lipid Peroxidation*
  • Oxidative Stress

Substances

  • Antioxidants