A new SH2D1A mutation in a female adult XLP disease with hemophagocytic lymphohistiocytosis and NK-cell leukemia

Jin-Hua Liang; Hua-Yuan Zhu; Dan-Min Xu; Li Wang; Yan Wang; Chun Qiao; Yu-Jie Wu; Rong Wang; Jian-Yong Li; Wei Xu

doi:10.1007/s00277-019-03810-y

A new SH2D1A mutation in a female adult XLP disease with hemophagocytic lymphohistiocytosis and NK-cell leukemia

Ann Hematol. 2019 Dec;98(12):2829-2831. doi: 10.1007/s00277-019-03810-y. Epub 2019 Nov 22.

Authors

Jin-Hua Liang^{1

2

3}, Hua-Yuan Zhu^{1

2

3}, Dan-Min Xu^{1

2

3}, Li Wang^{1

2

3}, Yan Wang^{1

2

3}, Chun Qiao^{1

2

3}, Yu-Jie Wu^{1

2

3}, Rong Wang^{1

2

3}, Jian-Yong Li^{1

2

3}, Wei Xu^{4

5

6}

Affiliations

¹ Department of Hematology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, 210029, China.
² Key Laboratory of Hematology of Nanjing Medical University, Nanjing, 210029, China.
³ Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, 210029, China.
⁴ Department of Hematology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, 210029, China. xuwei10000@hotmail.com.
⁵ Key Laboratory of Hematology of Nanjing Medical University, Nanjing, 210029, China. xuwei10000@hotmail.com.
⁶ Collaborative Innovation Center for Cancer Personalized Medicine, Nanjing, 210029, China. xuwei10000@hotmail.com.

PMID: 31758261
DOI: 10.1007/s00277-019-03810-y

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Adult
Female
Humans
Killer Cells, Natural*
Leukemia / genetics*
Lymphohistiocytosis, Hemophagocytic / genetics*
Lymphoproliferative Disorders / genetics*
Mutation*
Neoplasm Proteins / genetics*
Signaling Lymphocytic Activation Molecule Associated Protein / genetics*

Substances

Neoplasm Proteins
SH2D1A protein, human
Signaling Lymphocytic Activation Molecule Associated Protein