Peroxygenase-Catalysed Epoxidation of Styrene Derivatives in Neat Reaction Media

Abstract

Biocatalytic oxyfunctionalisation reactions are traditionally conducted in aqueous media limiting their production yield. Here we report the application of a peroxygenase in neat reaction conditions reaching product concentrations of up to 360 mM.

Keywords: Biocatalysis; Cascade reactions; Epoxidation; Neat reaction conditions; Peroxygenases.