Syphilis-Associated Acute Renal Failure and Hepatitis in the Setting of Human Immunodeficiency Virus Coinfection

Sex Transm Dis. 2019 Dec;46(12):816-818. doi: 10.1097/OLQ.0000000000001062.

Abstract

Two individuals with human immunodeficiency virus presented in acute renal failure with nephrotic range proteinuria and were diagnosed with secondary syphilis. One of them also had elevated transaminases. Kidney biopsies revealed membranous nephropathy, a rare complication of secondary syphilis, in both cases. Normal hepatic and renal function were restored after treatment with penicillin.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Acute Kidney Injury / diagnosis
  • Acute Kidney Injury / etiology*
  • Acute Kidney Injury / pathology
  • Acute Kidney Injury / physiopathology
  • Adult
  • Coinfection
  • Diagnosis, Differential
  • HIV Infections / complications*
  • HIV Infections / diagnosis
  • HIV Infections / pathology
  • HIV Infections / physiopathology
  • Hepatitis / diagnosis
  • Hepatitis / etiology*
  • Hepatitis / parasitology
  • Hepatitis / physiopathology
  • Humans
  • Male
  • Syphilis / complications*
  • Syphilis / diagnosis
  • Syphilis / pathology
  • Syphilis / physiopathology

Supplementary concepts

  • Syphilis, secondary