Can high resolution micro-ultrasound replace MRI in the diagnosis of prostate cancer?

Eur Urol Focus. 2020 Mar 15;6(2):419-423. doi: 10.1016/j.euf.2019.11.006. Epub 2019 Nov 24.


High resolution micro-ultrasound (micro-u/s) is a novel technology that permits visualization of lesions suspicious for prostate cancer. The resolution of 70 μ, that of a prostatic duct, means that alterations in ductal anatomy and cellular density are readily apparent. Initial experience in multiple centers comparing it to mpMRI suggests that the sensitivity for clinically significant prostate cancer is comparable or superior. Specificity is comparable or mildly reduced. Micro-u/s is an inexpensive, accessible and convenient alternative to mpMRI for imaging and diagnosing prostate cancer.

Keywords: High resolution micro ultrasound; Prostate cancer; Prostate imaging; Prostate ultrasound.

Publication types

  • Review

MeSH terms

  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Prostatic Neoplasms / diagnostic imaging*
  • Sensitivity and Specificity
  • Ultrasonography / methods