Cutaneous lupus erythematosus induced by drugs - novel insights

Expert Rev Clin Pharmacol. 2020 Jan;13(1):35-42. doi: 10.1080/17512433.2020.1698290. Epub 2019 Dec 2.


Introduction: There is a growing list of drugs implicated in inducing both subacute and chronic forms of cutaneous lupus erythematosus. It is important to recognize these drugs in order to quickly treat patients with drug induced disease.Areas covered: This paper reviews the current literature describing drugs implicated in causing cutaneous lupus erythematosus. A Pubmed search was used to compile a list of medications implicated up to August 2019. It reviews new classes of drugs identified as causing cutaneous lupus erythematosus, the pathophysiology of the disease process, and current recommendations for treatment of the disease.Expert opinion: Many drugs have been identified as inducing lupus, and many more continue to be described in new reports. Further research is needed to understand this phenomenon, which will aid in the diagnosis and treatment of affected patients.

Keywords: Drug induced lupus; chronic cutaneous lupus; cutaneous lupus diagnosis; cutaneous lupus erythematosus; cutaneous lupus treatment; subacute cutaneous lupus.

Publication types

  • Review

MeSH terms

  • Chronic Disease
  • Drug Eruptions / etiology*
  • Drug Eruptions / physiopathology
  • Humans
  • Lupus Erythematosus, Cutaneous / chemically induced*
  • Lupus Erythematosus, Cutaneous / physiopathology