When you hear hoofbeats, think horses and zebras: The importance of a wide differential when it comes to frontotemporal lobar degeneration

Milankumar Nathani; Vijaya Jaleel; Ana Turner; Caitlin Dirvonas; Uma Suryadevara; Rajiv Tandon

doi:10.1016/j.ajp.2019.101875

When you hear hoofbeats, think horses and zebras: The importance of a wide differential when it comes to frontotemporal lobar degeneration

Asian J Psychiatr. 2020 Jan:47:101875. doi: 10.1016/j.ajp.2019.101875. Epub 2019 Nov 7.

Authors

Milankumar Nathani¹, Vijaya Jaleel¹, Ana Turner¹, Caitlin Dirvonas¹, Uma Suryadevara², Rajiv Tandon¹

Affiliations

¹ University of Florida, 10348 SW 27th Pl, 32608, Gainesville, United States.
² University of Florida, 10348 SW 27th Pl, 32608, Gainesville, United States. Electronic address: suryadevara@ufl.edu.

PMID: 31775108
DOI: 10.1016/j.ajp.2019.101875

Abstract

Frontotemporal lobar degeneration (Frontotemporal dementia in DSM 4/FTD) is a progressive brain disease which frequently presents with neuropsychiatric symptoms. Prevalence of FTD is low, however the prognosis is poor. Early identification of FTD may improve quality of life, minimize behavioral disturbances and help with end of life planning. Diagnosis of FTD is often a diagnostic challenge as it has wide differentials. Authors discuss three clinical cases with their initial clinical presentation, diagnostic complexity and subsequent management.

Keywords: Frontotemporal lobar degeneration.

Published by Elsevier B.V.

Publication types

Case Reports

MeSH terms

Adult
Aged
Diagnosis, Differential
Frontotemporal Lobar Degeneration / diagnosis*
Humans
Male
Middle Aged