Vaccine-preventable meningitis in French children with incorrect vaccination status from 2011 to 2013

Arch Pediatr. 2020 Jan;27(1):1-5. doi: 10.1016/j.arcped.2019.10.008. Epub 2019 Nov 24.

Abstract

The objective of this study was to determine the number of cases of pediatric meningitis or purpura fulminans associated with an incorrect vaccination status from 2011 to 2013 in France. A total of 48 children with vaccine-preventable meningitis or purpura fulminans, including three deaths, had an incorrect vaccination status: 26 cases were due to Neisseria meningitidis group C (54.2%), 19 to Streptococcus pneumoniae (39.6%), and three to Haemophilus influenzae type b (6.3%). The majority of patients (n=35, 72.9%) had received no injection of the vaccine concerned. Over a 3-year period, 48 cases of bacterial meningitis or purpura fulminans in children could have been avoided if the French immunization schedule had been followed.

Keywords: Bacterial meningitis; Children; Vaccine.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Bacterial Vaccines
  • Child
  • Child, Preschool
  • Female
  • France / epidemiology
  • Haemophilus Vaccines
  • Haemophilus influenzae type b
  • Humans
  • Immunization Schedule*
  • Infant
  • Male
  • Meningitis, Bacterial / epidemiology*
  • Neisseria meningitidis
  • Prospective Studies
  • Purpura Fulminans / epidemiology
  • Streptococcus pneumoniae
  • Vaccination / statistics & numerical data*
  • Vaccine-Preventable Diseases / epidemiology*

Substances

  • Bacterial Vaccines
  • Haemophilus Vaccines