Regional assignment of the gene coding for human sucrase-isomaltase (SI) to chromosome 3q25-26

Ann Hum Genet. 1988 Jan;52(1):57-61. doi: 10.1111/j.1469-1809.1988.tb01077.x.

Abstract

The gene coding for sucrase-isomaltase (SI) has recently been mapped to chromosome 3 using a cDNA probe to analyse DNA from somatic cell hybrids (Green et al. 1987). We have now used this same cDNA probe to obtain a regional localization of this gene. In situ hybridization to normal metaphase chromosomes and to chromosomes from individuals with balanced translocations suggests a regional assignment to chromosome 3q25-26.

MeSH terms

  • Chromosome Mapping*
  • Chromosomes, Human, Pair 3*
  • DNA
  • Genes*
  • Humans
  • Hybrid Cells
  • Multienzyme Complexes / genetics*
  • Nucleic Acid Hybridization
  • Sucrase-Isomaltase Complex / genetics*

Substances

  • Multienzyme Complexes
  • DNA
  • Sucrase-Isomaltase Complex