Patients over Age 75 Are at Increased Risk of Emergency Department Visit and Hospitalization Following Colonoscopy

Dig Dis Sci. 2020 Jul;65(7):1964-1970. doi: 10.1007/s10620-019-05962-3. Epub 2019 Nov 29.

Abstract

Background: The age to stop screening or surveillance colonoscopy is not well established, and unplanned hospital use after colonoscopy in the elderly is not well understood.

Aims: To evaluate unplanned emergency department (ED) visits and hospitalization in patients over 75 within 7 days of outpatient colonoscopy.

Methods: In this retrospective, single-center, cohort study, we reviewed outpatient screening or surveillance colonoscopies in patients ≥ 50 in a tertiary care academic medical center or affiliated facility between January 2008 and September 2013. Colonoscopies were divided by age based on USPSTF recommendations. The rate of ED visits and hospitalizations per colonoscopy for each age-group was determined. Predictors of ED visit and hospitalization were assessed through univariate and multivariate logistic regressions, and mortality following colonoscopy was evaluated using Kaplan-Meier analysis.

Results: A total of 30,409 colonoscopies were performed in 27,173 patients (51% male) by 40 endoscopists. ED visits occurred after 188 colonoscopies (0.62%). Age over 75 years was independently associated with ED visit (OR 1.58, 95% CI 1.05-2.37, p = 0.027) and hospitalization (OR 3.7, 95% CI 2.03-6.73, p < 0.001) within 7 days of colonoscopy. Higher number of medication classes, recent ED visit, polypectomy, and endoscopic mucosal resection were also independent variables associated with ED utilization after procedure. The mortality rate at the end of the follow-up (median 4.4; IQR 2.7-6 years) was 1.9, 8.6, and 15.8% for the age-groups 50-75, 76-85, and > 85 years, respectively.

Conclusion: Patients over age 75 are 1.6 times as likely to use the ED and 3.7 times as likely to be hospitalized after colonoscopy. Further prospective studies are needed to assess the risk/benefit of nondiagnostic colonoscopy in geriatric patients.

Keywords: Colonoscopy; Complications; Geriatrics.

MeSH terms

  • Abdominal Pain / epidemiology*
  • Academic Medical Centers
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Ambulatory Surgical Procedures
  • Biopsy / statistics & numerical data
  • Colonic Polyps / surgery
  • Colonoscopy*
  • Colorectal Neoplasms / diagnosis*
  • Comorbidity
  • Early Detection of Cancer
  • Emergency Service, Hospital / statistics & numerical data*
  • Endoscopic Mucosal Resection / statistics & numerical data*
  • Fellowships and Scholarships
  • Female
  • Hospitalization / statistics & numerical data*
  • Humans
  • Kaplan-Meier Estimate
  • Logistic Models
  • Male
  • Middle Aged
  • Mortality
  • Multivariate Analysis
  • Postoperative Complications / epidemiology*
  • Postoperative Hemorrhage / epidemiology*
  • Retrospective Studies
  • Risk Factors
  • Tertiary Care Centers