Introduction: It is common that personality disorder (PD) co-occurs with major depressive disorder (MDD). In the current literature, there is a dearth of information on the co-occurrence of PD and MDD among Chinese population. Materials and Methods: 609 individuals were randomly sampled from outpatients diagnosed as MDD in Shanghai Mental Health Center. Co-morbidity of PDs was assessed using the Personality Diagnostic Questionnaire Fourth Edition Plus (PDQ-4+) and eligible subjects were interviewed with the Structured Clinical Interview for DSM-IV Axis II (SCID-II). The score of PDQ-4+ and the rate of SCID-II PD between subjects diagnosed with MDD and those with anxiety disorders (AD) were compared. Results: Two hundred fifty-eight outpatients (42.36%) with MDD were recognized to possess at least one criterion of diagnosis for PD, according to the DSM-IV. The most prevalent PD was depressive PD (14.61%), followed by avoidant (11.49%) and borderline (11.49%) PD. Cluster C PDs (anxious and panic PD) were the most common PD types (12.12%) when compared to other clusters. Compared to patients with AD, individuals with MDD were significantly more likely to have paranoid PD (6.6% vs. 3.3%, p = 0.011), borderline PD (11.5% vs. 3.7%, p = 0.000), passive-aggressive PD (5.6% vs. 2.4%, p = 0.007), and depressive PD (14.6% vs. 7.8%, p = 0.000). Discussion: The finding indicates that there is a high prevalence of PD among patients with MDD. More significant co-morbidity rates of PDs in MDD have been found when compared with AD. Further studies for the longitudinal impact of the PD-MDD co-morbidity are in need.
Keywords: China; anxiety disorders; co-morbidity; major depressive disorder; personality disorder.
Copyright © 2019 Zheng, Severino, Hui, Wu, Wang and Zhang.
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[Preliminary Comparative Study of the Personality Disorder Evaluation DIP Instrument With the Semi-Structured SCID-II Interview]C Massoubre et al. Encephale 35 (6), 544-53. PMID 20004285.The results must be interpreted with some care, considering the small number of patients. Important discrepancies were noticed between the diagnoses obtained through self …
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Demography of DSM-III Borderline Personality Disorder (PD): A Comparison With Axis II PDs, Affective Illness and Schizophrenia Convergent and Discriminant ValidationJM Taub. Int J Neurosci 82 (3-4), 191-214. PMID 7558649. - ReviewDemographic characteristics of borderline personality disorder (PD) defined according to DSM-III criteria were compared with those found for schizophrenia, affective illn …