Background: This study was conducted to determine the effects of sodium hexametaphosphate (SHMP) combined with other remineralizing agents on the staining and microhardness of early enamel caries.
Materials and methods: in This in vitro study The enamel buccal surfaces of 70 bovine incisors were classified into seven study groups (n = 10). Remineralizing agents were employed alone and in combination with SHMP in different groups, including: (1) 8% SHMP, (2) 2% sodium fluoride, (3) 2% sodium fluoride + SHMP, (4) Remin Pro®, (5) Remin Pro®+SHMP, (6) MI Paste Plus, and (7) MI Paste Plus + SHMP. A modified pH-cycling technique was used to reconstruct the dynamics of caries. Colorimetric and microhardness analyses were conducted before demineralization (T1), after caries formation (T2), and after the remineralizing treatment (T3). The data were analyzed by the one-way analysis of variance and the repeated measurement analysis (P > 0.05).
Results: After remineralizing cycles, the experimental groups treated with either SHMP alone or in combination with other materials showed less significant changes in the three variables of color (Δa, Δb, and ΔL) and the overall color change (ΔE). The enamel caries treated with Remin Pro® presented the highest color change, while Remin Pro®+ SHMP resulted in the least changes. The mean value of microhardness after remineralization improved significantly in all groups, except in the MI Paste Plus + SHMP group that showed the lowest value. In contrast, the highest microhardness value was recorded for Remin Pro®, being comparable to that of the sound teeth (P > 0.05).
Conclusion: SHMP, either alone or combined with remineralizing agents, created the least staining. Remineralizing materials alone showed higher surface hardness, while sodium fluoride alone showed higher surface hardness when combined with SHMP.
Keywords: Casein phosphopeptide-amorphous calcium phosphate; fluoride; remineralization; sodium hexametaphosphate.
Copyright: © 2019 Dental Research Journal.
Conflict of interest statement
The authors of this manuscript declare that they have no conflicts of interest, real or perceived, financial or non-financial in this article.
The Effect of Diode Laser Irradiation Associated With Photoabsorbing Agents Containing Remineralizing Materials on Microhardness, Morphology and Chemical Structure of Early Enamel CariesF Ahrari et al. J Clin Exp Dent 10 (10), e955-e962. PMID 30386500.The use of NaF either alone or combined with laser irradiation was the most effecttive strategy for increasing microhardness of WSLs. The application of diode laser throu …
Prevention of White Spot Lesions Using Three Remineralizing Agents: An in Vitro Comparative StudyS Tahmasbi et al. J Dent Res Dent Clin Dent Prospects 13 (1), 36-42. PMID 31217917.Background . Enamel demineralization around orthodontic brackets is an important clinical problem. This study sought to compare the efficacy of sodium fluor …
Effects of Treatment With Various Remineralizing Agents on the Microhardness of Demineralized Enamel SurfaceK Salehzadeh Esfahani et al. J Dent Res Dent Clin Dent Prospects 9 (4), 239-45. PMID 26889361.Background and aims. Remineralization of incipient caries is one of the goals in dental health care. The present study aimed at comparing the effects of casein phosphopep …
Effect of Remineralizing Agents on Tooth Color After Home BleachingM Malekipour et al. Front Dent 16 (3), 158-165. PMID 31858080.CPP-ACPF paste, Remin Pro paste, and 0.05% NaF mouthwash cause noticeable teeth discoloration immediately after bleaching. Remin Pro has less effect on tooth color than t …
Nanoparticles as Anti-Microbial, Anti-Inflammatory, and Remineralizing Agents in Oral Care Cosmetics: A Review of the Current SituationF Carrouel et al. Nanomaterials (Basel) 10 (1). PMID 31941021. - ReviewMany investigations have pointed out widespread use of medical nanosystems in various domains of dentistry such as prevention, prognosis, care, tissue regeneration, and r …
- Heymann HO, Swift EJ, Jr, Ritter AV. Sturdevant's Art and Science of Operative Dentistry. 6th ed. St. Louise: Mosby; 2014.
- Summitt JB, Schwartz RS, Hilton TJ, Robbins JW. Fundamentals of Operative Dentistry: A Contemporary Approach.3rd ed. 3rd ed. Hanover Park, Illinois: Quintessence Pub; 2006.
- Theodore M, Heymann HO, Edward J. Sturdevant's Art & Science of Operative Dentistry. 5th ed. St. Louise: Mosby; 2006.
- Fejerskov O, Nyvad B, Kidd E. Clinical and histological manifestations of dental caries. In: Fejerskov O, Kidd E, editors. Dental Caries: Disease and Its Clinical Management. New Jersey, Hoboken: Blackwell Pub; 2003. pp. 71–97.
- Ten Cate JM. In vitro studies on the effects of fluoride on de- and remineralization. J Dent Res. 1990;69:614–9. - PubMed