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Case Reports
. 2019 Dec;98(49):e18162.
doi: 10.1097/MD.0000000000018162.

Multiple Sites of Soft-Tissue Metastases Secondary to Lung Cancer: A Case Report

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Free PMC article
Case Reports

Multiple Sites of Soft-Tissue Metastases Secondary to Lung Cancer: A Case Report

Xingxing Zhu et al. Medicine (Baltimore). .
Free PMC article

Abstract

Rationale: The prognosis of lung cancer is dismal, which has resulted in lung carcinoma being one of the leading causes of cancer-related deaths worldwide. Non-small cell lung cancer accounts for approximately 80% of all types of lung carcinoma. The skeletal system and central nervous system are the most common distal metastatic sites in patients with lung cancer, while cutaneous and soft tissues metastasis is rare.

Patient concerns: We report a case of concomitant metastasis in the nasal tip and suspected buttocks metastasis secondary to lung cancer, who complained of repeated cough and white sputum for 6 months.

Diagnose: Primary lung cancer was diagnosed by bronchoscopy and biopsy, lesion on nasal tip was confirmed by biopsy. Furthermore, PET-CT scan identified the untouchable buttocks lesion that could have been easily missed.

Interventions: This patient refused systemic treatments, but he chose traditional Chinese medicine at home.

Outcomes: He died 6 months after the diagnosis.

Lessons: The possibility of metastasis of primary cancers should be considered when encountering soft-tissue neoplasm lesions, and a biopsy of the suspicious cutaneous lesions could likely aid in the histological identification of the primary cancer. PET-CT scan could be an effective supplementary tool for the diagnosis and evaluation of cancers.

Conflict of interest statement

The authors report no conflicts of interest.

Figures

Figure 1
Figure 1
The metastatic lesion on the patient's nasal tip. A round, painless erythematous nodule measuring 3.0 × 3.0 cm with a basal bulge could be observed on the nasal tip, with cutaneous capillary congestion and black hyperpigmentation.
Figure 2
Figure 2
Enhanced CT scan confirmed the existence of neoplasm in the left lower lobe. Red arrows indicate the location of the tumor.
Figure 3
Figure 3
The pathology of lung and nasal tip biopsy, both of which were confirmatory for low-grade differentiated squamous cell carcinoma. Scale bar: 50 μm.
Figure 4
Figure 4
PET-CT scan of the patient, which revealed the nasal tip and suspected buttock metastasis of primary lung cancer. A, whole body scan; B–D, skull, lung, and buttocks scan, respectively, hypermetabolic activities were seen in these areas.

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