Computational analysis of continuous body temperature provides early discrimination of graft-versus-host disease in mice

Blood Adv. 2019 Dec 10;3(23):3977-3981. doi: 10.1182/bloodadvances.2019000613.


  1. Unsupervised machine learning analysis of continuous body temperature data revealed early signals of aGVHD in allo-HCT mice.

  2. Continuous measurement of body temperature is promising for early prediction of aGVHD in human allo-HCT patients.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Body Temperature
  • Graft vs Host Disease
  • Hematopoietic Stem Cell Transplantation / methods*
  • Humans
  • Mice
  • Transplantation Conditioning / methods*
  • Transplantation, Homologous / methods*