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, 10 (4), 396-401

A 25-year Trend in Gastrointestinal Cancers in Northern Iran (1991-2016)


A 25-year Trend in Gastrointestinal Cancers in Northern Iran (1991-2016)

Hakimeh Mehdizadeh et al. Caspian J Intern Med.


Background: Identifying the incidence of cancer helps in planning and prioritizing resources for its screening, prevention, treatment and diagnosis. This study aimed at investigating a 25-year trend in gastrointestinal cancer in northern Iran during 1991-2016.

Methods: This research was a trend analysis. The study population was one thousand five hundred and thirty-five cancer patients referring to Shahid Rajai Hospital in Babolsar, northern Iran, as the only center for radiotherapy in the North of Iran, during 1991-2016. SPSS version 22 was used for entering data and t-test, ᵡ2 and ANOVA were used for analyzing data in the significant level of ≤0.05.

Results: The highest incidence of stomach cancer was 111 (35%) in 2011 and the lowest incidence was 44 (16.3%) in 1996, The highest frequency of esophageal cancer was reported 137(56.1%) cases in 1991 and the lowest frequency was 78 (26.3%) cases in 2016, while the highest incidence of colorectal cancer was 109 (36.7%) cases in 2016 and its lowest frequency was 32 (16.3%) in 1996. There was also a significant difference in the frequency of gastrointestinal cancers in different studied years (p <0.001).

Conclusion: The trends in the incidence of stomach and colorectal cancers in northern Iran were increasing while esophageal cancer was decreasing.

Keywords: Colorectal cancer; Esophageal cancer; Gastrointestinal cancer; Incidence.

Conflict of interest statement

Nothing to declare.


Figure 1
Figure 1
The trends of gastrointestinal cancers between 1991-2016 based on the frequencies of patients referring to the hospital
Figure 2
Figure 2
The trend of incidence of gastrointestinal cancers in northern Iran among the rural and urban regions and rural and urban men and women
Figure 3
Figure 3
The mean age of patients referring to the hospital center based on the studied year, gender and cancer type during 1991-2016

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