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Case Reports
, 2019, 3284258

Alveolar Hemorrhage, a Rare and Life-Threatening Complication of Catastrophic Antiphospholipid Syndrome

Case Reports

Alveolar Hemorrhage, a Rare and Life-Threatening Complication of Catastrophic Antiphospholipid Syndrome

Grace Loza et al. Case Rep Rheumatol.


Alveolar hemorrhage is the rarest pulmonary complication of catastrophic antiphospholipid syndrome and is associated with high mortality risk. This life-threatening complication results from autoimmune damage to the alveolar blood vessels. Given the limited literature addressing the association of these two pathologies, we report a series of three cases with this complication and then compare our findings with 6 cases reported in the literature.

Conflict of interest statement

The authors declare that they have no conflicts of interest.


Figure 1
Figure 1
(a) Chest X-ray; AP view: bilateral, diffuse basal and perihilar alveolar infiltrate; (b) chest CT: bilateral effusion, increased vascularity, with bilateral infiltrates that converges to the posterior area.
Figure 2
Figure 2
(a) Chest X-ray; AP view: diffuse infiltrate redistributed to the bases; (b) chest CT: diffuse bilateral alveolar infiltrate.
Figure 3
Figure 3
Chest CT: bilateral alveolar infiltrates in a ground-glass pattern.

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