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. 2019 Dec 4;11(12):1944.
doi: 10.3390/cancers11121944.

Surgical Management of Hepatoblastoma and Recent Advances

Free PMC article

Surgical Management of Hepatoblastoma and Recent Advances

Tianyou Yang et al. Cancers (Basel). .
Free PMC article


Hepatoblastoma is the most common childhood liver malignancy. The management of hepatoblastoma requires multidisciplinary efforts. The five-year overall survival is approximately 80% in developed countries. Surgery remains the mainstay of treatment for hepatoblastoma, and meticulous techniques must be employed to ensure safe and effective local control surgeries. Additionally, there have been several advances from both pediatric and adult literature in the way liver tumor surgery is performed. In this review, we highlight important aspects of liver surgery for hepatoblastoma, the management of metastatic disease, and the most current technical advances in performing these procedures in a safe and effective manner.

Keywords: children; hepatoblastoma; liver resection; metastasectomy.

Conflict of interest statement

All authors declare no conflict of interest.


Figure 1
Figure 1
Virtual 3D simulation in a case of segment 8 segmentectomy (Adopted from [50]). The tumor is located in segment 8 of the liver (a). S8 segmentectomy was planned, and the resection line was drawn along the demarcation line of segment 8 portal vein (b). An image of virtual resection of segment 8 (c). The position of the stump of the segment 8 portal vein and the running directions of the middle hepatic vein and the right hepatic vein were similar to those seen in the preoperative simulation (d).
Figure 2
Figure 2
Indocyanine green (ICG) guided thoracoscopic surgery. Green color indicates lung metastasis.

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