Trichoblastoma of lid: a masquerading tumour

BMJ Case Rep. 2019 Dec 8;12(12):e232599. doi: 10.1136/bcr-2019-232599.

Abstract

A 62-year-old woman came to our hospital with complaints of painless gradual increase in dark coloured mass along inner canthus of the right eye. The surface of the mass was rough with a well-defined margin. No other systemic abnormality was detected. Wide margin excision was done and the excised mass was sent for histopathological examination. No skin grafting was done and the raw area was left for self-healing. In the next 3 weeks, skin growth over the raw area was observed and it was cosmetically acceptable. Histopathological examination revealed well-circumscribed tissue composed of aggregation of basaloid cells suggestive of trichoblastoma. Immunohistochemistry revealed positive staining of CD34 and CD10. Trichoblastoma is a rare entity seen in our clinical practice. Hence, a patient presenting with darker masses trichoblastoma can be considered as differential diagnosis.

Keywords: ophthalmology; pathology; skin cancer.

Publication types

  • Case Reports

MeSH terms

  • Antigens, CD34 / analysis
  • Biomarkers, Tumor / analysis
  • Carcinoma, Basal Cell / diagnosis*
  • Diagnosis, Differential
  • Eyelid Neoplasms / diagnosis*
  • Eyelid Neoplasms / pathology
  • Eyelid Neoplasms / surgery
  • Female
  • Hair Follicle / pathology*
  • Hair Follicle / surgery
  • Humans
  • Immunohistochemistry
  • Middle Aged
  • Neprilysin / analysis
  • Treatment Outcome

Substances

  • Antigens, CD34
  • Biomarkers, Tumor
  • Neprilysin