The ocular ischemic syndrome. Clinical, fluorescein angiographic and carotid angiographic features

Int Ophthalmol. 1988 Feb;11(4):239-51. doi: 10.1007/BF00131023.


The records of 43 consecutive patients (51 eyes) with the ocular ischemic syndrome (ocular symptoms and signs attributable to severe carotid artery obstruction) were studied in a retrospective fashion. Men comprised 67% of the group and the mean age at presentation was 64.5 years. In the anterior segment, neovascularization of the iris was observed in 66% of eyes and iritis was noted in 18%. Posterior segment signs included narrowed retinal arteries and dilated, but not tortuous, retinal veins. Mid-peripheral retinal hemorrhages were seen in 80% of eyes, posterior segment neovascularization was observed in 37%, and a cherry red spot was noted in 12%. Fluorescein angiography commonly revealed delayed choroidal and retinal filling, while electroretinography generally demonstrated a reduction in the amplitude of both the a- and b-waves.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Angiography
  • Carotid Arteries / diagnostic imaging
  • Carotid Artery Diseases / complications
  • Eye / blood supply*
  • Female
  • Fluorescein Angiography
  • Glaucoma, Neovascular / complications
  • Humans
  • Iris Diseases / complications
  • Ischemia / complications*
  • Ischemia / diagnostic imaging
  • Ischemia / pathology
  • Male
  • Middle Aged
  • Pain
  • Retinal Diseases / complications
  • Uveitis / complications